Caf1R gene and its role in the regulation of capsule formation of Y. pestis

FEBS Letters

Zav'yalov, V.P.¹  Karlyshev, A.V.¹  Abramov, V.M.¹  Galyov, E.E.¹ 

[1] Institute of Immunology, State Concern ‘Biopreparation’, 142380 Lyubuchany, Moscow Region, Russia

关键词: Gene regulation;    Capsule antigen;    Nucleotide sequence;    Y. pestis;   

DOI  :  10.1016/0014-5793(92)80650-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A new transcription unit of the f1 gene cluster was found. The DNA sequencing revealed one long open reading frame. Deletion and frame shift mutation analyses have demonstrated the importance of a corresponding gene product for the F1 antigen biosynthesis. A homology of the deduced amino acid sequence with that of AraC family DNA-binding regulators was shown. A potential regulatory DNA region is discussed.

【 授权许可】

Unknown