A new gene of the ƒ1 operon of Y. pestis involved in the capsule biogenesis

FEBS Letters

Zav'yalov, V.P.¹  Karlyshev, A.V.¹  Smirnov, O.Yu.¹  Abramov, V.M.¹  Guzayev, A.P.¹  Galyov, E.E.¹ 

[1] Institute of Immunology, State Concern ‘Biopreparation’, 142380 Lyubachany, Moscow Region, USSR

关键词: Capsular antigen;    Protein secretion;    Nucleotide sequence;    Complementation analysis;    Y. pestis;   

DOI  :  10.1016/0014-5793(92)80331-A

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The DNA sequence determination or the ƒ1 operon between the genes encoding the F1 subunit (caf1) and chaperone-like protein (caf1M) revealed a large open reading frame that codes for a polypeptide similar to some E. coli proteins involved in the biogenesis of fimbria. The deletion and in trans complementation analyses showed that this gene is not necessary for extracellular transport or the F1 subunit but plays a role in the capsule assembly.

【 授权许可】

Unknown