The 65‐kDa protein from pig heart A new substrate for Clostridium botulinum ADP‐ribosyltransferase (exoenzyme C3)

FEBS Letters

Hoffenberg, Simon I.¹  Kurochkin, Iliya N.¹  Tkachuk, Vsevolod A.³  Rybin, Vitalyi O.³  Efimenko, Alexander N.² 

[1] USSR Research Center for Molecular Diagnostics and Therapy, Moscow, USSR;Research Institute for Epidemiology and Microbiology, Moscow, USSR;USSR Cardiology Research Center, Moscow, USSR

关键词: ADP-ribosyltransferase;    GTP-binding protein;    Pig heart sarcolemma;    Clostridium botulinum;   

DOI  :  10.1016/0014-5793(91)81152-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In the pig heart sarcolemma, a 65 kDa protein is found to be ADP-ribosylated by Clostridium botulinum ADP-ribosyltransferase (exoenzyme C₃). ADP-ribosylation of this protein is regulated by guanyl nucleotides and cytosol factor in a fashion similar to that for other C₃ substrates. The new exoenzyme C₃ substrate was partially purified. This protein is supposed to be a GTP-binding one.

【 授权许可】

Unknown