FEBS Letters | |
Cloning of segment polarity gene homologues from the unsegmented brachiopod Terebratulina retusa (Linnaeus) | |
Holland, Peter W.H.1  Lanfear, Jeremy1  Williams, Nicola A.1  | |
[1] Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK | |
关键词: Engrailed; Homeobox; Zinc finger gene; Wingless; Brachiopod; Molecular evolution; | |
DOI : 10.1016/0014-5793(91)81286-H | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
We have used the polymerase chain reaction (PCR) to amplify, clone and sequence homologues of the Drosophila segment polarity genes engrailed (en), cubitus interruptus Dominant (ciD ) and wingless (wg) from the genome of the brachiopod, Terebratulina retusa (Linnaeus). The deduced translation products of brachiopod en and ciD share high levels of sequence identity with their Drosophila homologues. The brachiopod wg-related clone is divergent from Drosophila wg, although clearly a member of the wg/Wnt gene family. These results indicate that structural diversity of Drosophila segment polarity genes has been evolutionarily conserved in a divergent, ancient and unsegmented animal phylum.
【 授权许可】
Unknown
【 预 览 】
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RO201912020295462ZK.pdf | 296KB | download |