Mechanical influence and cAMP injection evoke the same reaction of neuron ionic channels

FEBS Letters

Myakotina, Olga L.¹  Avdonin, Vladimir B.¹  Minina, Svetlana V.¹  Liberman, Efim A.¹ 

[1] Institute for Information Transmission Problems, Acad. Sci. USSR, Ermolova str. 19, Moscow 101447, USSR

关键词: Cyclic AMP;    Cytoskeleton;    Neuron ionic channel;    Patch-clamp technique;    Helix lucorum;   

DOI  :  10.1016/0014-5793(91)81075-J

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Intracellular cAMP injection and negative pressure in the patch-electrode increase the interburst closed time of the same potassium ionic channels in the snail neuron membrane. Sodium channels which were registered as change of background noise are activated both by cAMP injection and by negative pressure. These results are considered in connection with data about the unusual biochemistry of the neuron reaction to cAMP.

【 授权许可】

Unknown