The organization of the gene for the human cerebroside sulfate activator protein

FEBS Letters

Holtschmidt, Hans²  Sandhoff, Konrad²  Fürst, Werner²  Schnabel, Doris²  Suzuki, Kunihiko¹  Kwon, Hae Young² 

[1] Brain and Development Research Center, Departments of Neurology and Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA;Institut für Organische Chemie und Biochemie der Universität Bonn, D-5300 Bonn 1, Germany

关键词: Cerebroside sulfate activator protein;    Genomic structure;    Alternative splicing;    CSAP;    cerebroside sulfate activator protein;   

DOI  :  10.1016/0014-5793(91)80308-P

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The organization of 14 exons covering 97% of the cDNA sequence of human cerebroside sulfate activator protein precursor has been determined from two overlapping EMBL-4 human genomic clones extending over 17kb. All exons and exon/intron splice junctions and five introns were sequenced. Exon 8 consists of only 9 bp and is involved in alternative splicing which generates three different mRNAs of cerebroside sulfate activator precursor.

【 授权许可】

Unknown