Amino acid sequences of nerve growth factors derived from cobra venoms

FEBS Letters

Oda, Toshio²  Ikeda, Kiyoshi²  Inoue, Seiji²  Koyama, Junichi²  Hayashi, Kyozo¹ 

[1] Department of Pharmacology, Gifu Pharmaceutical University, Gifu 502, Japan;Department of Biochemistry, Osaka University of Pharmaceutical Sciences, Kawai, Matsubara, Osaka 580, Japan

关键词: Amino acid sequence;    Nerve growth factor;    Naja naja;    Naja naja siamensis;    NGF;    nerve growth factor;    HPLC;    high-performance liquid chromatography;    PE;    S-pyridylethyl;    PEC;    S-pyridylethylcysteine;    N;    amino;    C;    carboxyl;   

DOI  :  10.1016/0014-5793(91)80244-W

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Amino acid sequences of nerve growth factors (NGFs), purified from the venoms of Indian cobra (Naja naja) and Thailand cobra (Naja naja siamensis) were determined. The sequence of N. naja NGF differed from that reported previously by Hogue-Angeletti et. al. [(1976) Biochemistry 15, 26–34]. The sequence of N. naja siamensis NGF was identical to that of Formosan cobra Naja naja atra NGF, determined previously by Oda et. al. [(1989) Biochem, Int. 19, 909–917] and to that deduced from the nucleotide sequence of an NGF cDNA from the venom gland of N. naja siamensis, as reported by Selby et. al. [(1987) J. Neurosci. Res. 18, 293–298].

【 授权许可】

Unknown