Modification methylase M.Sau3239I from Streptomyces aureofaciens 3239

FEBS Letters

Zelinková, E.¹  Pauliček, M.¹  Zelinka, J.¹ 

[1] Institute of Molecular Biology, Slovak Academy of Sciences, Dúbravská 21, 84251 Bratislava, Czechoslovakia

关键词: Streptomyces aureofaciens;    DNA methylation;    Modification methylase;   

DOI  :  10.1016/0014-5793(90)80393-W

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

By chromatography on phosphocellulose and Heparin-Sepharose the modification methylase M.Sau3239I was detected and partly purified from cells of Streptomyces aureofaciens 3239. Methylation by this enzyme protects DNA from cleavage by the restriction endonuclease R.Sau3239I. The enzyme catalyzes methylation of adenine to N-6-methyladenine in the 5'-CTCG^mAG-3' recognition sequence.

【 授权许可】

Unknown