Analysis of the stop codon context in plant nuclear genes

FEBS Letters

Angenon, Geert¹  Depicker, Ann¹  Van Montagu, Marc¹ 

[1] Laboratorium voor Genetica, Rijksuniversiteit Gent, B-9000 Gent, Belgium

关键词: Compilation;    Codon context;    Stop codon;    Translation termination;   

DOI  :  10.1016/0014-5793(90)80392-V

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A region of 18 nucleotides surrounding the stop codon (the stop codon context) in 748 plant nuclear genes was analyzed. Non-randomness was found both upstream and downstream from the stop codon, suggesting that these sequences may help in ensuring efficient termination of translation. The UAG amber codon is the least-used stop codon and the bias in the nucleotide distribution 5' and 3' to the stop codon was more pronounced for the amber codon than for the other stop codons. This might indicate that the codon context affects termination more at UAG than at UGA or UAA stop codons.

【 授权许可】

Unknown