2‐Deoxy‐D‐glucose resistant yeast with altered sugar transport activity

FEBS Letters

D'Amore, Tony¹  Stewart, Graham G.¹  Novak, Srdjan¹ 

[1] Brewing Research Department, John Labatt Limited, 150 Simcoe Street, London, Ont., Canada N6A 4M3

关键词: Sugar transport;    2-Deoxy-D-glucose;    Glucose;    Maltose;    Yeast;   

DOI  :  10.1016/0014-5793(90)81154-G

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The transport of glucose and maltose in Saccharomyces cerevisiae was observed to occur by both high and low affinity transport systems. A spontaneously isolated 2-deoxy-D-glucose resistant mutant was observed to transport glucose and maltose only by the high affinity transport systems. Associated with this was an increase in the V _max values, indicating derepression of the high affinity transport systems. The low affinity transport systems could not be detected. This mutant will be important in examining the repression regulatory and sugar transport mechanisms in yeast.

【 授权许可】

Unknown