Novel features of retroviruses associated with human diseases

FEBS Letters

Chandra, Angelika¹  Chandra, Prakash¹  Gerber, Thomas¹ 

[1] Laboratory of Molecular Biology (ZBC), University Medical School, Theodor-Stern-Kai 7, Frankfurt 71, FRG

关键词: Leukemia/lymphoma virus;    Immunodeficiency virus;    Accessory gene;    Reverse transcriptase;    Transactivation;   

DOI  :  10.1016/0014-5793(90)81296-Z

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The last decade has witnessed a new chapter in the history of retrovirology. As of now, four human retroviruses have been identified and molecularly characterized. They are associated with a wide spectrum of human diseases including cancer, immunodeficiency and neurological disorders. By virtue of their clinical relevance, their novel genes and regulatory mechanisms these viruses have become the focal point of research in retrovirology. The study of these viruses is of fundamental importance in understanding the mechanisms leading to transformation of human cells and distortion of the immunological state.

【 授权许可】

Unknown