Crystallization of blood coagulation factor XIII by an automated procedure

FEBS Letters

Karges, Hermann E.²  Liesum, Alexander¹  Storm, Rüdiger¹  Metzner, Hubert J.²  Hilgenfeld, Rolf¹ 

[1] Hoechst Aktiengesellschaft, P.O.B. 800320, D-6230 Frankfurt 80, FRG;Behringwerke Aktiengesellschaft, P.O.B. 1140, D-3550 Marburg, FRG

关键词: Blood coagulation factor XIII;    Transglutaminase;    Protein crystallization;    Crystallization robotic;    X-ray crystallography;   

DOI  :  10.1016/0014-5793(90)80896-Q

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Both recombinant blood coagulation factor XIII a-chain and factor XIII isolated from human placenta have been crystallized using a novel robotic system for the automatic screening of crystallization conditions. The monoclinic and orthorhombic crystals obtained are suitable for X-ray analysis.

【 授权许可】

Unknown