A numerical model of protein crystallization with counter diffusion method

3rd International School and Conference on Optoelectronics, Photonics, Engineering and Nanostructures (Saint Petersburg OPEN 2016)

Sokolovskiy, A.S.^1 ; Trushin, Yu V.^1 ; Lubov, M.N.^1 ; Eliseev, I.E.^1 ; Yudenko, A.N.^1 ; Dubina, M.V.^1

Nanobiotech Lab., St. Petersburg Academic University, St. Petersburg

194021, Russia^1

关键词: Counter diffusion;    Crystallization process;    Developed model;    Numerical solution;    Protein crystallization;    Protein lysozyme;    Theoretical modeling;   

Others  :  https://iopscience.iop.org/article/10.1088/1742-6596/741/1/012053/pdf
DOI  :  10.1088/1742-6596/741/1/012053

来源: IOP

【 摘 要 】

A theoretical model is presented to simulate the growth and nucleation of protein lysozyme crystals by counter diffusion method. The comparison of experimental and simulation results shows that the numerical solution accurately describes the initial stages of crystallization. The developed model can be used to describe crystallization processes with various counter diffusion experiment parameters.