Fatty acid acylation of lens fiber plasma membrane proteins

FEBS Letters

Manenti, Stéphane¹  Dunia, Irène¹  Benedetti, E.Lucio¹ 

[1] Institut Jacques Monod, Université Paris VII, CNRS, Tour 43, 2 place Jussieu, 75251 Paris Cedex 05, France

关键词: Fatty acylation;    Lens fiber;    MP26;    a-crystallin;   

DOI  :  10.1016/0014-5793(90)80228-B

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We describe in this report the fatty acylation of some of the main polypeptides from the eye lens fibers. MP26, the major lens fiber plasma membrane protein, and probably MP22, its natural degradation product, are palmitoylated in a post-translational process. This is also the case for α-crystallin, a major cytoplasmic structural protein shown to interact directly with the plasma membrane. Furthermore, a 65 kDa non-identified polypeptide and a high molecular weight component are also modified in the same way.

【 授权许可】

Unknown