N‐Terminal sequence similarities between components of the multicatalytic proteinase complex

FEBS Letters

Davison, Matthew D.¹  Lilley, Kathryn S.¹  Rivett, A.Jennifer¹ 

[1] Department of Biochemistry, University of Leicester, Leicester, UK

关键词: Multicatalytic proteinase;    Protease;    Gene family;    (Rat liver);    PTH;    phenylthiohydantoin;    PVDF;    polyvinylidene-difluoride;    SDS;    sodium dodecyl sulphate;   

DOI  :  10.1016/0014-5793(90)80220-D

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The multicatalytic proteinase complex is a high molecular weight nonlysosomal proteinase which is composed of many different types of subunit. As part of a study of the possible relationships between subunits, polypeptides derived from the multicatalytic proteinase from rat liver have been subjected to N-tenninal amino acid sequence analysis. Although several of the subunits are blocked at their N-termini, sequences have been obtained for 7 of the polypeptides. Each of the 7 sequences is unique but they show considerable sequence similarity, suggesting that the proteins are encoded by members of the same gene family.

【 授权许可】

Unknown