期刊论文详细信息
FEBS Letters | |
Rapid up‐ and down‐regulation of hexokinase II in rat skeletal muscle in response to altered contractile activity | |
Weber, Franz E.1  Pette, Dirk1  | |
[1] Fakultät für Biologie, Universität Konstanz, D-7750 Konstanz, FRG | |
关键词: Contractile activity; Hexokinase II; Protein synthesis; Fast-twitch muscle; (Rat); | |
DOI : 10.1016/0014-5793(90)80574-3 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
An up to 14-fold increase in total hexokinase activity induced by low-frequency stimulation in rat fast-twitch muscle was followed by a rapid decay in enzyme activity after cessation of stimulation. In vivo labeling revealed that these alterations were related to rapid changes in [35S]methionine incorporation into hexokinase II. A recovery period of 15 h after cessation of stimulation was sufficient to normalize the approximately 30-fold elevated [35S]methionine incorporation.
【 授权许可】
Unknown
【 预 览 】
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RO201912020293090ZK.pdf | 335KB | download |