Kinetoplast DNA‐aggregating proteins from the parasitic protozoan Crithidia fasciculata

FEBS Letters

Tittawella, Ivor¹ 

[1] Department of Microbiology, University of Umeå, 901 87 Umeå, Sweden

关键词: DNA-aggregating protein;    Kinetoplast DNA;    (Crithidia fasciculata);   

DOI  :  10.1016/0014-5793(90)80065-Q

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Proteins from C. fasciculata, which preferentially aggregate the parasite's AT-rich mitochondrial (kinetoplast) DNA in vitro, are reported. The aggregation is non-topological, non-covalent, independent of Mg²⁺ and ATP, but much improved by spennidine. We discuss how these proteins might modulate the shape and size of the parasite's mitochondrial genome.

【 授权许可】

Unknown