Electrostatic coupling between membrane proteins

FEBS Letters

Brown, Guy C.¹ 

[1] Department of Biochemistry, University of Cambridge, Tennis Court Rd., Cambridge CB2 1QW, England

关键词: Membrane protein;    Electric field;    intramembrane;    Bioenergetics;    Signal transduction;    Ion channel;   

DOI  :  10.1016/0014-5793(90)80051-J

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Charges on membrane proteins are argued to produce very large electric fields within the membrane which may be felt by neighbouring membrane proteins. The activity of many membrane proteins may be sensitive to the electric field in the membrane; thus one membrane protein may affect the activity of another via the local electric field without any contact between the two. More specific electrostatic interactions are possible with binding between the two proteins. The possible roles of such interactions in bioenergetics, neurophysiology and signal transduction are discussed.

【 授权许可】

Unknown