Effect of adenosine on fructose 2,6‐bisphosphate levels and glucose metabolization by chicken erythrocytes

FEBS Letters

Espinet, Carme¹  Bartrons, Ramon¹  Carreras, José¹ 

[1] Departament de Ciéncies Fisiològiques, Humanes i de la Nutrició, Unitat de Bioquímica, Facultat de Medicina, Universitat de Barcelona, Zona Universitària de Pedralbes, 08028 Barcelona, Spain

关键词: Adenosine;    Fructose 2;    6-bisphosphate;    Erythrocyte;    (Chicken);   

DOI  :  10.1016/0014-5793(89)81635-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Adenosine can be metabolized by chicken erythrocytes as a carbon source maintaining ATP levels. In addition, it stimulates glucose uptake and lactate production. Adenosine effects do not involve binding to membrane receptors. They are dependent on the provision of a carbon source to glycolysis and correlate with the increase of fructose 2,6-bisphosphate levels that activating phosphofructokinase would increase the glycolytic flux.

【 授权许可】

Unknown