Brain‐specific expression of transthyretin mRNA as revealed by cDNA cloning from brain

FEBS Letters

Goto, Sataro¹  Motojima, Kiyoto¹ 

[1] Department of Biochemistry, School of Pharmaceutical Sciences, Toho University, Chiba 274, Japan

关键词: Transthyretin;    Prealbumin;    Nucleotide sequence;    Brain-specific expression;    Alternative promoter;    (Rat brain);   

DOI  :  10.1016/0014-5793(89)81625-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

cDNAs for rat transthyretin mRNA were cloned from a brain cDNA library. Sequencing analyses showed the presence of an additional 5' sequence that had not been reported for the liver mRNA corresponding to the flanking promoter region of the gene. This additional sequence was expressed only in the brain, suggesting the presence of a brain-specific promoter.

【 授权许可】

Unknown