期刊论文详细信息
FEBS Letters | |
Human Na+, K+ ‐ATPase genes | |
Petrukhin, K.E.1  Bessarab, D.A.1  Sverdlov, E.D.1  Modyanov, N.N.1  Monastyrskaya, G.S.1  Orlova, M.Yu.1  Ushkaryov, Yu.A.1  Nikiforova, N.N.1  Broude, N.E.1  | |
[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, 117871 Moscow, USSR | |
关键词: ATPase; Na+; K+-; β-Subunit; Family of gene; Exon/intron structure; Pseudogene sequence; | |
DOI : 10.1016/0014-5793(89)81591-1 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The existence of a chromosome gene family containing at least one gene and one pseudogene was shown for the Na+,K+-ATPase β-subunit. A partial structure of the βI-gene was determined, the coding part of which was completely homologous to cDNA of the Na+ K+-ATPase βI-subunit from HeLa cells [8]. The region encoding the putative protein transmembrane domain was shown to be bordered by two introns. The structure of a pseudogene (βψ) was determined. This pseudogene is processed and contains multiple stop codons. Its homology to the βI-subunit cDNA from HeLa cells is about 88%.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201912020292766ZK.pdf | 496KB | download |