Family of human Na+,K+‐ATPase genes Structure of the putative regulatory region of the α+‐gene

FEBS Letters

Petrukhin, K.E.¹  Smirnov, Yu.V.¹  Bessarab, D.A.¹  Sverdlov, E.D.¹  Modyanov, N.N.¹  Monastyrskaya, G.S.¹  Ushkaryov, Yu.A.¹  Malyshev, I.V.¹  Broude, N.E.¹ 

[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, 117871 Moscow, USSR

关键词: ATPase;    Na+;    K+-;    Subunit;    α+-catalytic;    Gene sequence;    Regulatory region;   

DOI  :  10.1016/0014-5793(89)80588-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The primary structure of the putative regulatory region of a gene of the Na⁺,K⁺-ATPase multigene family in the human genome has been determined. This region includes the first exon with all of the untranslatable sequence of mRNA and a dozen nucleotides, coding for the first four amino acids of the hypothetic precursor of the α⁺-subunit. The entire region comprises over 1400 bp. The possible role of specific nucleotide blocks within this region in comparison with other genes is discussed.

【 授权许可】

Unknown