期刊论文详细信息
FEBS Letters | |
S‐100a0 protein stimulates Ca2+ ‐induced Ca2+ release from isolated sarcoplasmic reticulum vesicles | |
Aisa, M.C.2  Giambanco, I.2  Donato, R.2  Marsili, V.1  Angelella, P.1  Fanò, G.1  | |
[1] Institute of Cell Biology, Faculty of Sciences, University of Perugia, 06100 Perugia, Italy;Section of Anatomy, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, 06100 Perugia, Italy | |
关键词: Protein S-100a0; Ca2+ release; Regulation; (Muscle cell); | |
DOI : 10.1016/0014-5793(89)81127-5 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
S-100a0 protein, the αα-isoform of the S-100 family, stimulates Ca2+ -induced Ca2+ release from terminal cisternae isolated from rat skeletal muscle cells. The stimulatory effect of S-100a0 is maximal at ∼5 μM S-100a0 and half maximal at ∼0.1 μM S-100a0, at 1.8 μM free Ca2+ in the presence of 5 mM Mg2+ plus 0.1 M KCl. The effect of the protein on Ca2+ -induced Ca2+ release is completely inhibted by the calcium release blocker, ruthenium red.
【 授权许可】
Unknown
【 预 览 】
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