期刊论文详细信息
FEBS Letters
S‐100a0 protein stimulates Ca2+ ‐induced Ca2+ release from isolated sarcoplasmic reticulum vesicles
Aisa, M.C.2  Giambanco, I.2  Donato, R.2  Marsili, V.1  Angelella, P.1  Fanò, G.1 
[1] Institute of Cell Biology, Faculty of Sciences, University of Perugia, 06100 Perugia, Italy;Section of Anatomy, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, 06100 Perugia, Italy
关键词: Protein S-100a0;    Ca2+ release;    Regulation;    (Muscle cell);   
DOI  :  10.1016/0014-5793(89)81127-5
学科分类:生物化学/生物物理
来源: John Wiley & Sons Ltd.
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【 摘 要 】

S-100a0 protein, the αα-isoform of the S-100 family, stimulates Ca2+ -induced Ca2+ release from terminal cisternae isolated from rat skeletal muscle cells. The stimulatory effect of S-100a0 is maximal at ∼5 μM S-100a0 and half maximal at ∼0.1 μM S-100a0, at 1.8 μM free Ca2+ in the presence of 5 mM Mg2+ plus 0.1 M KCl. The effect of the protein on Ca2+ -induced Ca2+ release is completely inhibted by the calcium release blocker, ruthenium red.

【 授权许可】

Unknown   

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