期刊论文详细信息
FEBS Letters | |
Monitoring the transport and phosphorylation of 2‐deoxy‐D‐glucose in tumor cells in vivo and in vitro by 13C nuclear magnetic resonance spectroscopy | |
Lyon, Robbe C.1  Cohen, Jack S.1  Kaplan, Ofer1  Navon, Gil1  | |
[1] Medicine Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA | |
关键词: NMR; 13C-; Deoxy-D-glucose; 2-; Phosphorylation; Transport; Labeling; 13C; Glycolysis; (Cancer cell; Tumor); | |
DOI : 10.1016/0014-5793(89)81246-3 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
We describe the use of 2-deoxy-D-[6-13C]glucose to follow simultaneously, by 13C NMR, both transport and phosporylation to its 6-phosphate form, in MCF-7 breast cancer cells in vitro and in vivo in subcutaneous tumors in nude mice.
【 授权许可】
Unknown
【 预 览 】
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