Electrostimulation‐induced fast‐to‐slow transitions of myosin light and heavy chains in rabbit fast‐twitch muscle at the mRNA level

FEBS Letters

Heilig, Annegard¹  Härtner, Karl-Thomas¹  Pette, Dirk¹  Kirschbaum, Bernhard J.¹ 

[1] Fakultät für Biologie, Universität Konstanz, D-7750 Konstanz, FRG

关键词: Fast-twitch muscle;    Myosin light chain isoform;    Myosin heavy chain isoform;    mRNA;    Chronic electrostimulation;   

DOI  :  10.1016/0014-5793(89)80112-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Chronic low-frequency stimulation of rabbit fast-twitch muscle induces progressive increases in slow myosin light chain mRNAs followed by an increase in the slow myosin heavy chain HCI mRNA. Therefore, the effects of chronic stimulation are more pronounced in rabbit than in rat fast-twitch muscle. The latter responds mainly with a rearrangement of its fast isomyosin pattern.

【 授权许可】

Unknown