Architectonics of a bacterial flagellin filament subunit

FEBS Letters

Kostyukova, A.S.¹  Fedorov, O.V.¹  Pyatibratov, M.G.¹ 

[1] Institute of Protein Research, Academy of Sciences of the USSR, 142292 Pushchino, Moscow Region, USSR

关键词: Flagellin;    Immunology;    Polymerization;    Predicted structure;    (Escherichia coli);   

DOI  :  10.1016/0014-5793(88)81048-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Flagellins of two Escherichia coli strains and their tryptic fragments were studied by different methods. Probabilities of secondary structure formation were also calculated for all flagellins with a known primary structure. The obtained data permit one to suggest a model for the flagellin molecule consisting of a central part responsible for antigenic properties and terminals responsible for polymerization. The central part is variable in length from a few amino acid residues to three-four hundred depending on the bacterial species. The terminal parts consist of about 160 amino acid residues from the N-end and 100 from the C-end.

【 授权许可】

Unknown