Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes

FEBS Letters

Mishina, Masayoshi¹  Maeda, Akito¹  Numa, Shosaku¹  Kubo, Tai¹ 

[1] Departments of Medical Chemistry and Molecular Genetics, Kyoto University Faculty of Medicine, Kyoto 606, Japan

关键词: Muscarinic acetylcholine receptor subtype;    RNA blot hybridization analysis;    (Exocrine gland;    Smooth muscle;    Heart;    Cerebrum);    mAChR;    muscarinic acetylcholine receptor;   

DOI  :  10.1016/0014-5793(88)80947-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The tissue distribution of the mRNAs encoding muscarinic acetylcholine receptors (mAChRs) I, II, III and IV has been investigated by blot hybridization analysis with specific probes. This study indicates that exocrine glands contain both mAChR I and III mRNAs, whereas smooth muscles contain both mAChR II and III mRNAs. All four mAChR mRNAs are present in cerebrum, whereas only mAChR II MRNA is found in heart.

【 授权许可】

Unknown