Na+, K+‐ATPase: Tissue‐specific expression of genes coding for α‐subunit in diverse human tissues

FEBS Letters

Petrukhin, K.E.¹  Sverdlov, E.D.¹  Modyanov, N.N.¹  Monastyrskaya, G.S.¹  Akopyanz, N.S.¹  Broude, N.E.¹ 

[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, Moscow, USSR

关键词: Na+;    K+-ATPase;    Catalytic subunit;    Isoform;    Tissue-specific expression;   

DOI  :  10.1016/0014-5793(88)80546-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The expression of genes coding for α and αiii isoforms of Na⁺,K⁺-ATPase α-subunit has been studied in human kidney, brain, thyroid and liver cells. The expression was shown to be subjected to a tissue-specific control and also depended on the developmental stage. The tissue-specific expression of genes coding for different isoforms of the catalytic subunit of Na⁺,K⁺-ATPase perhaps may be attributed to various functions of proteins belonging to this family.

【 授权许可】

Unknown