Stop making sense or Regulation at the level of termination in eukaryotic protein synthesis

FEBS Letters

Morch, Marie-Dominique¹  Valle, Rosaura P.C.¹ 

[1] Institut Jacques Monod, 2 Place Jussieu, 75251 Paris Cedex 05, France

关键词: Viral gene expression;    Nonsense suppression;    Frameshift;    suppressor tRNA;    Protein synthesis termination;    Translational accuracy;    AIDS;    acquired immunodeficiency syndrome;    AlMV;    alfalfa mosaic virus;    BLV;    bovine leukemia virus;    BNYVV;    beet necrotic yellow vein virus;    bp;    base pair;    CaMV;    cauliflower mosaic virus;    CarMV;    carnation mottle virus;    FeLV;    feline leukemia virus;    HIV-1;    human immunodeficiency virus type 1;    HTLV I;    human T-cell leukemia virus type I;    HTLV II;    human T-cell leukemia virus type II;    IBV;    infectious bronchitis virus;    nt;    nucleotide;    LTSV;    lucerne transient streak virus;    Mo-MuLV;    Moloney murine leukemia virus;    MMTV;    mouse mammary tumor virus;    MPMV;    Mason Pfizer monkey virus;    ORF;    open reading frame;    P-Ser;    phosphoserine;    RaMuLV;    Rauscher murine leukemia virus;    RF;    release factor;    RSV;    Rous sarcoma virus;    Se-Cys;    selenocysteine;    TMV;    tobacco mosaic virus;    TRV;    tobacco rattle virus;    TYMV;    turnip yellow mosaic virus;    SBWMV;    soil-borne wheat mosaic virus;   

DOI  :  10.1016/0014-5793(88)81225-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

An increasing number of examples of translational regulation at the level of termination has been recently reported in eukaryotes. This paper reviews our present knowledge on this topic and proposes an understanding of these regulations by relating the study of viral gene expression to a comprehensive view of the mechanisms and components of the translational process.

【 授权许可】

Unknown