期刊论文详细信息
FEBS Letters | |
Atrial natriuretic peptide (ANP) in rat gastrointestinal tract | |
Vuolteenaho, O.2  Nikkilä, L.2  Ruskoaho, H.1  Leppäluoto, J.2  Vakkuri, O.2  Maksniemi, T.2  Puurunen, J.1  Kangas, J.2  Arjamaa, O.2  | |
[1] Departments of Pharmacology, University of Oulu, 90220 Oulu, Finland;Departments of Physiology, University of Oulu, 90220 Oulu, Finland | |
关键词: Natriuretic peptide; Radioimmunoassay; (Rat; Stomach; Intestine); ANP; atrial natriuretic peptide; BSA; bovine serum albumin; HPLC; high-performance liquid chromatography; IR; immunoreactive; PMSF; phenylmethylsulphonyl fluoride; RIA; radioimmunoassay; TFA; trifluoroacetic acid; V 0; void volume; | |
DOI : 10.1016/0014-5793(88)81359-0 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
Acid extracts of rat stomach and small intestine contained 8.6 ± 3.7 and 39 ± 15 ng/g of immunoreactive atrial natriuretic peptide (ANP). When studied by gel filtration and reverse-phase high-performance liquid chromatography, the stomach immunoreactivity consisted of multiple components, whereas the small intestine contained mostly proANP and ANP 1–28-like material. These findings indicate that ANP may have a role in the physiology of the gastrointestinal tract, e.g. in the regulation of water and electrolyte absorption.
【 授权许可】
Unknown
【 预 览 】
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