The mechanism of cytochrome oxidase and other reaction centres for electron/proton pumping

FEBS Letters

Williams, R.J.P.¹ 

[1] University of Oxford, Inorganic Chemistry Laboratory, South Parks Road, Oxford OX1 3QR, England

关键词: Cytochrome oxidase;    Copper;    Iron;    Proton pumping;    Helix dynamics;    Dioxygen;   

DOI  :  10.1016/0014-5793(87)80539-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The functional significance of the metal centres of cytochrome oxidase is deduced from the ways in which the centres are bound into its peptides. To this end use is made of structural knowledge of other metallo-proteins for dioxygen binding, haemocyanin and haemoglobin, and for electron transfer, cytochromes b and azurin. The order and manner in which the motions of helical sections of the oxidase are linked to proton pumping are suggested and a comparison is made with other proton pumps, for example that of ATP synthetases.

【 授权许可】

Unknown