Similarities between a predicted secondary structure for the M1 RNA ribozyme and the tRNA binding center of 16 S rRNA from E. coli

FEBS Letters

Boehm, Siegfried¹ 

[1] Central Institute of Molecular Biology, Department of Molecular Biophysics, Academy of Sciences of the GDR, 1115 Berlin-Buch, GDR

关键词: M1 RNA;    16 S rRNA;    Ribozyme;    Secondary structure;    Substrate recognition;    tRNA binding;   

DOI  :  10.1016/0014-5793(87)80830-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We propose a new model for the secondary structure of the M1 RNA component of E. coli RNase P which is based on significant sequence homologies with parts of the E. coli 16 S rRNA. A large domain of the new model resembles closely the secondary structure of the tRNA binding center of 16 S rRNA. We suggest that this domain of M1 RNA when functioning as a ribozyme binds the mature part of the precursor tRNA.

【 授权许可】

Unknown