Neuromedin N: Presence and chromatographic characterization in the rat

FEBS Letters

Ball, J.A.¹  Bloom, S.R.¹  Reece, D.¹  Lee, Y.C.¹ 

[1] Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, Du Cane Road, London W12 OHS, England

关键词: Neuromedin N;    Neurotensin;    Chromatography;    Neuropeptide distribution;    (Rat peripheral tissue);   

DOI  :  10.1016/0014-5793(87)80913-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The distribution of neuromedin N and its structurally related peptide, neurotensin, was investigated in the rat and found to be remarkably similar with highest concentrations in the ileum. However, neuromedin N but not neurotensin was found in the kidney. Chromatographic analysis of immunoreactive neuromedin N demonstrated a single peak of immunoreactivity which was distinguishable from the single peak of immunoreactive neurotensin. Neuromedin N is likely to be a naturally occurring peptide and is distinct from neurotensin in rat peripheral tissues.

【 授权许可】

Unknown