Donor and acceptor splice signals within an exon of the human fibronectin gene: a new type of differential splicing

FEBS Letters

Vibe-Pedersen, Karen¹  Baralle, Francisco E.²  Magnusson, Staffan¹ 

[1] Department of Molecular Biology and Plant Physiology, C.F. Møllers Alle 130, University of Aarhus, DK 8000 Aarhus C, Denmark;Sir William Dunn School of Pathology, South Parks Road, Oxford University, Oxford OX1 3RE, England

关键词: Fibronectin gene clone;    Differential splicing;    Nonhomologous connective strand;    FN;    fibronectin;    ED;    extra domain;    IIICS;    type III connecting strand;    kbp;    kilobasepair;   

DOI  :  10.1016/0014-5793(86)81506-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have sequenced that area of a human fibronectin gene clone which codes for a connecting strand separating the last two areas of the type III homology. The gene has a complex exon with two ‘AG’ acceptor sites. One of these can be used (exon subdivision). In addition 93 basepairs inside the exon are sometimes spliced out as an intron. This is the third differential splicing found in the fibronectin gene transcript and it represents a new type of differential splicing.

【 授权许可】

Unknown