Ribonuclease‐sensitive δ‐aminolevulinic acid formation from glutamate in cell extracts of Methanobacterium thermoautotrophicum

FEBS Letters

Thauer, R.K.¹  Friedmam, H.C.¹ 

[1] Fachbereich Biologie, Philipps-Universität, Karl-von-Frisch-Straβe, D-3550 Marburg, FRG

关键词: C5 pathway;    Aminolevulinic acid synthesis;    (Archaebacteria);    Tetrapyrrole biosynthesis;   

DOI  :  10.1016/0014-5793(86)80017-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Cell extracts of Methanobacterium thermoautotrophicum, which form δ-aminolevulinic acid (ALA) via the C₅ pathway, catalyzed the synthesis of ALA from glutamate in an ATP-dependent reaction. The activity was abolished by incubation of the extract with ribonuclease. The mechanism of ALA synthesis in this methanogenic archaebacterium thus appears to be similar to that found in algae and in higher plants.

【 授权许可】

Unknown