Identification and quantitation of O‐phosphoserine in human plasma fibronectin

FEBS Letters

Etheredge, R.E.¹  Glimcher, M.J.¹  Fossel, E.¹  Tanzer, M.L.²  Han, S.² 

[1] Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopedic Surgery, Harvard Medical School and Children's Hospital, 300 Longwood Avenue, Boston, MA02115, U.S.A.;Department of Biochemistry, University of Connecticut, Farmington, CT 06032, USA

关键词: O-Phosphoserine;    Plasma fibronectin;    Degradation;   

DOI  :  10.1016/0014-5793(85)80720-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

O-Phosphoserine was positively identified as the phosphorylated moiety in human plasma fibronectin by ³¹P-NMR of intact peptides. These data correlated completely with chemical analyses which demonstrated the presence of O-phosphoserine at a concentration of 2 residues/molecule. Neither O-phosphothreonine nor O-phosphotyrosine was detected in partial acid and partial alkaline hydrolysates, respectively.

【 授权许可】

Unknown