Postnatal developmental profiles of filamentous actin and of 200 kDa neurofilament polypeptide in the visual cortex of light‐ and dark‐reared rats and their relationship to critical period plasticity

FEBS Letters

Cronly-Dillon, J.R.¹  Nona, S.N.¹  Trowell, S.C.¹ 

[1] Department of Ophthalmic Optics, University of Manchester Institute of Science and Technology, Manchester M60 1QD, England

关键词: Development;    Cytoskeleton;    Plasticity;    PMSF;    phenylmethylsulphonyl fluoride;    PCMB;    p-chloromercuribenzoic acid;   

DOI  :  10.1016/0014-5793(85)81350-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The concept of critical period plasticity in rat visual cortex has been studied in terms of changes in the level of filamentous actin and of the 200 kDa neurofilament polypeptide. Our results suggest that the postnatal developmental profile of filamentous actin is affected by visual experience, as a consequence of eye-opening. No such correlation, however, is detected for the 200 kDa neurofilament polypetide. The significance of these findings in relationship to neuronal plasticity is discussed in terms of changes in the state and equilibrium conditions of the cytoskeletal proteins.

【 授权许可】

Unknown