NMR solution structure of gramicidin A complex with caesium cations

FEBS Letters

Barsukov, Igor L.¹  Bystrov, Vladimir F.¹  Arseniev, Alexander S.¹ 

[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, UI. Miklukho-Maklaya 16/10, Moscow V-437, USSR

关键词: Double helix;    Gramicidin A;    Ion channel;    Metal complex;    NMR;    Peptide conformation;   

DOI  :  10.1016/0014-5793(85)80225-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The conformation of the 1:1 complex of [Val¹] gramicidin A with caesium cations has been determined in methanol/chloroform (1:1) solution by 2-dimensional ¹H-NMR spectroscopy. The molecular structure was found to be a right-handed antiparallel double helical dimer ↑↓ππ_LD ^7.2 with 7.2 residues per turn, which incorporates two caesium cations.

【 授权许可】

Unknown