Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

FEBS Letters

Falck, J.R.²  Capdevila, J.¹  Snijder, G.D.² 

[1] Departments of Biochemistry, University of Texas Health Science Center, Dallas, TX 75235, USA;Departments of Physiology, University of Texas Health Science Center, Dallas, TX 75235, USA

关键词: Arachidonic acid;    Epoxygenase;    Anterior pituitary;    Epoxyeicosatrienoic acid;   

DOI  :  10.1016/0014-5793(84)80625-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

【 授权许可】

Unknown