The decarboxylation of 3‐mercaptopyruvate to 2‐mercaptoacetate

FEBS Letters

Nilsson, Lennart¹  Sörbo, Bo¹  Mårtensson, Johannes¹ 

[1] Department of Clinical Chemistry, University of Linköping, S-581 85 Linköping, Sweden

关键词: 3-Mercaptopyruvate;    2-Mercaptoacetate;    α-Ketoacid decarboxylase;    Acyl CoA hydrolase;   

DOI  :  10.1016/0014-5793(84)81191-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Rat brain mitochondria were found to convert 3-mercaptopyruvate to 2-mercaptoacetate in the presence of NAD⁺ coenzyme A and thiamin pyrophosphate. The overall reaction probably consists of an oxidative decarboxylation of 3-mercaptopyruvate with 2-mercaptoacetyl CoA as a product which is then hydrolyzed to 2-mercaptoacetate by acyl CoA hydrolase

【 授权许可】

Unknown