期刊论文详细信息
FEBS Letters | |
The competitive equilibrium between aluminium and ferric ions for the binding sites of transferrin | |
Cochran, M.1  Neoh, S.1  Coates, J.1  | |
[1] Department of Medicine and Immunology, Flinders Medical Centre, Bedford Park, 5042 Australia | |
关键词: Human transferrin; Aluminium binding constant; Molar relationship; Aluminium-iron competition; OD240; optical density at 240 nm; | |
DOI : 10.1016/0014-5793(84)80926-6 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
Human transferrin is shown to bind 2 mol of aluminium per mol of protein using spectrophotometric titration. Competitive equilibrium between aluminium and ferric ions for transferrin binding sites is observed, and a value of 2.5 (± 0.4) × 1015 M−1 is found for the apparent binding constant under physiological conditions.
【 授权许可】
Unknown
【 预 览 】
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