Identity of dihydrodiol dehydrogenase and 3α‐hydroxysteroid dehydrogenase in rat but not in rabbit liver cytosol

FEBS Letters

Oesch, Franz¹  Wörner, Walter¹ 

[1] Institut für Toxikologie, Obere Zahlbacher Strasse 67, D-6500 Mainz, FRG

关键词: Dihydrodiol dehydrogenase;    3α-Hydroxysteroid dehydrogenase;    Aldo/keto reductase;    Activity staining;    Medroxyprogesterone acetate;   

DOI  :  10.1016/0014-5793(84)81325-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Dihydrodiol dehydrogenase and 3α-hydroxysteroid dehydrogenase activity in rat and rabbit liver cytosol have been analyzed by isoelectric focussing and subsequent activity staining. Identity of the two enzymes in rat liver cytosol is demonstrated. At least 4 main enzyme forms possessing dihydrodiol dehydrogenase activity can be detected in rabbit liver cytosol. However, in this species, only one of these forms has measurable activity towards 3α-hydroxysteroids.

【 授权许可】

Unknown