A novel super‐secondary structure of proteins and the relation between the structure and the amino acid sequence

FEBS Letters

Efimov, A.V.¹ 

[1] Institute of Protein Research, USSR Academy of Sciences, 142292 Pushchino, Moscow Region, USSR

关键词: Super-secondary structure;    α-Helix;    Polypeptide chain conformation;    Amino acid sequence;    Packing of α-helix;    Embryo of folding;   

DOI  :  10.1016/0014-5793(84)80039-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A novel protein super-secondary structure which is referred to as an αα-corner is considered. The αα-corner is formed by two consecutive α-helices packed approximately crosswise and connected by two or more peptide units. It is shown that the amino acid sequences coding for the αα-corners have a strictly definite order of hydrophobic, hydrophilic and glycine residues. A hypothesis is suggested that the αα-corner can be an embryo of protein folding.

【 授权许可】

Unknown