Heterogeneous turnover of terminal and core sugars within the carbohydrate chain of dipeptidylaminopeptidase IV isolated from rat liver plasma membrane

FEBS Letters

Volk, Brigitte A.¹  Kreisel, Wolfgang¹  Gerok, Wolfgang¹  Reutter, Werner²  Köttgen, Eckart¹ 

[1] Medizinische Klinik der Albert-Ludwigs-Universität, D-7800 Freiburg, FRG;Institut für Molekularbiologie und Biochemie der Freien Universität, Dahlem, D-1000 Berlin 33, Germany

关键词: Plasma membrane;    Glycoprotein;    Dipeptidylaminopeptidase IV;    Intramolecular heterogeneous turnover;    D-Mannose;    D-Glucosamine;   

DOI  :  10.1016/0014-5793(83)81183-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Dipeptidylaminopeptidase IV, a plasma membrane-bound glycoprotein, is characterized by an intramolecular hetereneous turover of the protein backbone and carbohydrate chain. The faster turnover of the latter is restricted only to the outer sugars. The inner core sugars D-mannose and N-acetyl-D-glucosamine turn over at the same rate as the protein backbone

【 授权许可】

Unknown