Evidence for the presence of N 2‐(1,3‐dicarboxypropyl)‐L‐amino acids in crown‐gall tumors induced by Agrobacterium tumefaciens strains 181 and EU6

FEBS Letters

Chen, Chong-Maw¹  Chang, Chi-Cheng¹ 

[1] Department of Life Science and Biomedical Research Institute, University of Wisconsin-Parkside, PO Box 2000, Kenosha, WI 53141, USA

关键词: Asparaginopine;    Glutaminopine;    Agrobacterium tumefaciens;    Crown-gall;    Tumor;    Ti-plasmid;   

DOI  :  10.1016/0014-5793(83)80802-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Using crown-gall tumors induced by Agrobacterium tumefaciens strains 181 and EU6 several unusual compounds have been isolated in a single fraction. Physicochemical analysis of the compounds in this fraction showed that they are N ²-(1,3-dicarboxypropyl)-L-amino acids derived from neutral and acidic amino acids. Asparagine and glutamine derivatives (asparaginopine and glutaminopine) are the main components. Synthesis of asparaginopine from asparagine, α-ketoglutarate and NADPH, and degradation of asparaginopine to asparagine have also been demonstrated using enzyme prepared from Pinto bean strain 181 tumor.

【 授权许可】

Unknown