Evidence that the α2HS glycoprotein receptor and the Epstein‐Barr virus nuclear antigen (EBNA) are identical

FEBS Letters

André, C.M.¹  Lewis, J.G.¹ 

[1] Department of Clinical Biochemistry, Christchurch Hospital, Christchurch, New Zealand

关键词: α2HS glycoprotein receptor;    Epstein—Barr virus;    Epstein—Barr virus nuclear antigen (EBNA);    Lymphocyte;   

DOI  :  10.1016/0014-5793(83)81030-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Evidence is presented which suggests that the α₂HS glycoprotein (α₂HS) receptor on lymphocytes transformed by Epstein—Barr virus (EBV) and the EBV-determined nuclear antigen (EBNA) are immunologically related, and may be identical. Western blotting, using both anti-EBNA and anti-α₂HS receptor serum identified a similar M _r 48 000 component in labelled detergent-solubilized transformed cell supernatants. The M _r 48 000 component recognized by anti-EBNA serum had a pI between 7–8, similar to that reported for the α₂HS receptor.

【 授权许可】

Unknown