Epoxide hydrolase activity in isolated peroxisomes of mouse liver

FEBS Letters

Alfred, Völkl¹  Françoise, Bieri²  Philip, Bentley²  Fahimi, Hussein D.¹  Waechter, Felix²  Willy, Stäubli² 

[1] Department of Anatomy, II. Division, University of Heidelberg, 69 Heidelberg, FRG;CIBA-GEIGY Limited, Basle, Switzerland

关键词: Epoxide hydrolase;    Peroxisome;    Subcellular distribution;    TSO;    trans-stilbene oxide;   

DOI  :  10.1016/0014-5793(83)80583-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Using trans-stilbene oxide as substrate, the subcellular distribution of epoxide hydrolase was investigated in livers from DBA/2 mice. The highest specific activities were found in cytosolic and light mitochondrial fractions. Isopycnic subfractionation of the light mitochondrial fraction showed that the organelle-bound trans-stilbene oxide hydrolase is localized in peroxisomes.

【 授权许可】

Unknown