Characterization of the permeability increase induced by the incorporation of glycophorin in phosphatidylcholine vesicles

FEBS Letters

de Kruijff, Ben¹  du Maine, Atala P.M.¹  van Hoogevest, Peter¹ 

[1] Department of Biochemistry and Institute of Molecular Biology, State University of Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands

关键词: Glycophorin;    Dioleoylphosphatidylcholine;    Vesicle;    Bilayer permeability;    Pore size;   

DOI  :  10.1016/0014-5793(83)81112-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Glycophorin incorporation into large unilamellar dioleoylphosphatidylcholine vesicles results in a greatly increased bilayer permeability for non-electrolytes of M _r-values up to 900. This suggests that glycophorin aggregates induce the formation of pores with a 15–18 Å diameter.

【 授权许可】

Unknown