Restoration by insulin of the responsiveness of stimulated adipocytes to adenosine

FEBS Letters

Jacquemin, Claude¹  Lambert, Bernard¹ 

[1] Laboratoire de Biochimie, Faculté des Sciences, B.P. no. 347, 51062 Reims-Cédex, France

关键词: Adipocyte;    Adenylate-cyclase;    Lipolysis;    Adenosine Insulin;   

DOI  :  10.1016/0014-5793(83)80202-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The stimulation of adipocyte-cyclase by isoproterenol decreases its sensitivity to adenosine, with, as a consequence, a decrease in its antilipolytic effect. The presence of insulin under conditions where its action on the phosphodiesterase activity is impaired, restores the responsiveness of adenylate-cyclase and of lipolysis to adenosine.

【 授权许可】

Unknown