Changes in transcriptional activity of chronically stimulated fast twitch muscle

FEBS Letters

Heilig, Annegard¹  Pette, Dirk¹ 

[1] Fakultät für Biologie, Universität Konstanz, Postfach 5560, D-7750 Konstanz, FRG

关键词: Fast and slow twitch muscle;    Chronic stimulation;    mRNA;    In vitro translation;    Myosin light chain;   

DOI  :  10.1016/0014-5793(83)80071-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

mRNAs extracted from rabbit soleus, normal and 28-day, indirectly stimulated tibialis anterior muscles were translated in an in vitro system. Analysis for translation products by 2-dimensional electrophoresis showed fast myosin light chains in tibialis anterior, and slow myosin light chains in soleus muscle. The stoichiometry of the in vitro translated light chain varies from that seen in normal fast and slow twitch muscles. The stimulated muscle contained mRNA coding, both for fast and slow myosin light chains, although the pattern of slow myosin light chains appears not to be complete at this point of time of the transformation process.

【 授权许可】

Unknown